Chemistry: natural resins or derivatives; peptides or proteins; – Peptides of 3 to 100 amino acid residues – 25 or more amino acid residues in defined sequence
Reexamination Certificate
2006-07-04
2006-07-04
Chan, Christina (Department: 1644)
Chemistry: natural resins or derivatives; peptides or proteins;
Peptides of 3 to 100 amino acid residues
25 or more amino acid residues in defined sequence
C530S325000, C530S326000, C530S327000, C530S328000, C530S329000, C530S330000
Reexamination Certificate
active
07071299
ABSTRACT:
The complement system plays an important role in providing resistance to infections and in the pathogenesis of tissue injury. Yet an inappropriate activation of complement can result in a variety of disorders. The present invention provides C1s catalytic site-directed moieties, C1s exosite binding moieties, and bivalent polypeptide inhibitors comprising such moieties, which can be used to treat conditions characterized by inappropriate complement activation.
Fox Brian A.
Sheppard Paul O.
West Robert R.
Chan Christina
Jones Phillip B. C.
Lewis Michelle L.
VanderVegt F. Pierre
ZymoGenetics Inc.
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