Peptide and peptolide substrates for mammalian collagenase

Details Peptide and peptolide substrates for mammalian collagenase Peptide and peptolide substrates for mammalian collagenase

1982-04-08

1984-04-17

Phillips, Delbert R.

Chemistry of carbon compounds

Miscellaneous organic carbon compounds

C-metal

435 23, C07C10352, C12Q 138

Patent

active

044433670

ABSTRACT:
The disclosure relates to novel synthetic peptide and peptolide substrates having high activity for the enzyme collagenase. These substrates have the following amino acid sequences:

REFERENCES:
patent: 4138394 (1979-02-01), Sakakibara et al.
patent: 4176009 (1979-11-01), Sakakibara et al.
Nagai et al., Biochimica, Biophysica Acta 445, 521-524, (1976).
Masui et al., Biochem. Med. 17, 215-221, (1977).

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