Chemistry: molecular biology and microbiology – Micro-organism – tissue cell culture or enzyme using process... – Recombinant dna technique included in method of making a...
Patent
1987-03-09
1992-06-02
Schwartz, Richard A.
Chemistry: molecular biology and microbiology
Micro-organism, tissue cell culture or enzyme using process...
Recombinant dna technique included in method of making a...
4352523, 4353201, 43525233, 536 27, 514 12, 514869, A61K 3702, C12P 2100, C12N 1500, C12N 1512, C07K 714
Patent
active
051186152
ABSTRACT:
Disclosed is a DNA fragment comprising a base sequence coding for a peptide occurring in human atrium cordis and having diuretic action or a precursor of the peptide, plasmids containing the DNA fragment, microorganisms transformed with the plasmid, and a process for production of the peptide using the transformant.
Also disclosed is a new peptide consisting of 126 amino acids occurring in human atrium cordis and a precursor thereof. The peptide has notable diuretic action and hypotensive or antihypertensive actions.
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Hayashi Yujiro
Kangawa Kenji
Matsuo Hisayuki
Nakazato Hiroshi
Oikawa Shinzo
Nolan S. L.
Schwartz Richard A.
Suntory Limited
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