Peptide analog

Details Peptide analog Peptide analog

1991-10-07

1999-06-01

Tsang, Cecilia J.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Peptide containing doai

514 17, 514 18, 514 19, 530328, 530329, 530330, A61K 3804, C07K 500, C07K 1600, C07K 1700

Patent

active

059088320

ABSTRACT:
The present invention relates to an analog of Neuropeptide FF (e.g., daY8Ra) and to a pharmaceutical composition containing same. The invention further relates to methods of using the analog to attenuate the effects of drug addiction, drug tolerance, drug dependence or of abstinence syndrome.

REFERENCES:
Charpentier, et al, Peptides, vol. 9, pp. 835-841, 1988.
Majane, et al, Peptides, vol. 8 pp. 657-662, 1987.
Majane, et al Peptides vol. 9 pp. 1137-1144, 1988.
Yang, et al Proc. Natl. Acad. Sci, vol. 82, pp. 7757-7761, 1985.
Tang, et al, Proc. Natl. Acad. Sci vol. 81, pp. 5002-5005, 1984.
Malin et al, Peptides, vol. 11, pp. 969-972, 1990.
Malin, et al, Peptides, vol. 11 pp. 277-280, 1990.
Payza, et al, J. Pharmacology and Experimental Therapeutics, vol. 267, No. 1, pp. 88-94. 1993.
Malin et al, Life Sciences, vol. 53. PL 261-266, 1993.

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