Peptide affinity labels for thrombin and other trypsin-like prot

Details Peptide affinity labels for thrombin and other trypsin-like prot Peptide affinity labels for thrombin and other trypsin-like prot

1980-04-25

1982-03-09

Phillips, Delbert R.

Drug, bio-affecting and body treating compositions

Immunoglobulin, antiserum, antibody, or antibody fragment,...

Reduced antigenicity, reduced ability to bind complement, or...

546231, 2601125R, 260239A, A61K 3700, C07D23700, C07D 0000, C07C10352

Patent

active

043189040

ABSTRACT:
A peptide affinity label of the formula (I): ##STR1## wherein X is a radical capable of acting as a leaving group in a nucleophilic substitution reaction;

REFERENCES:
patent: 3884896 (1975-05-01), Blomback et al.
patent: 4061625 (1977-12-01), Ekenstam et al.
Kirby, et al., Biochemistry, vol. 18, pp. 3564-3570 (1979).
Kettner & Shaw in "Chemistry and Biology of Thrombin", edited by Lundblad, Fenton/Mann, 1977, 129-143.
Kettner/Shaw, Biochemistry 17, 4778-4784 (1978).
Bajusz, et al., Peptides: Chemistry, Structure, Biology, 603-608, 1975.

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