Peptic ulcer treatment method

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Ester doai

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Details

514927, 514573, 514690, 514678, A61K 31215

Patent

active

047074957

ABSTRACT:
A method of treating peptic ulcer disease by topical application of a prostaglandin analog is described.

REFERENCES:
patent: 4097603 (1978-06-01), Robert
patent: 4198521 (1980-04-01), Floyd et al.
patent: 4210669 (1980-07-01), Shimomura
patent: 4254145 (1981-03-01), Birnbaum
Birnbaum J. E., Chan P. S., Cervoni P.: Cutaneous Erythema and Blood Pressure Lowering Effects of Topically Applied 16-Vinylprostaglandins, Prostaglandins 23: 185-199, 1982.
Cervoni P., Chan P. S., Lie F. M., Birnbaum J. E.: CL 115,347 (DHV-PGE.sub.2 ME): A New Orally and Topically Active Prostaglandin Antihypertensive Agent, Federation Proc. 42:157-161, 1983.
Hunt J. N., Smith J. L., Jiang C. L., Kessler L.: Effect of a Synthetic Prostaglandin E.sub.1 Analog on Aspirin-Induced Gastric Bleeding and Secretion, Dig Dis Sci 28: 897-902, 1983.
Reele S. B., Bohan D.: Oral Antisecretory Activity of Prostaglandin E.sub.2 in Man, Dig Dis Sci 29: 390-393, 1984.
Robert A.: Prostaglandins: Their Effect on the Digestive System, Viewpoints on Digestive Disease 2:1-4, 1979.
Robert A., Nezamis H. E., Lancaster C., Hanchar A. J.: Cytoprotection by Prostaglandins in Rats, Prevention of Gastric Necrosis Produced by Alcohol, HCl, NaOH, Hypertonic NaCl, and thermal Injury, Gastroenterology 77: 433-443, 1979.
Shay H., Sun D. C., Gruenstein M.: A Quantitative Method for Measuring Spontaneous Gastric Secretion in Rat, Gastroenterology 26: 906-913, 1954.
Johansson C., Bergstrom S.: Prostaglandins and Protection of the Gastroduodenal Mucosa, Scand J Gastroenterol, Suppl. nr 77, 17: 21-46, 1982.

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