Organic compounds -- part of the class 532-570 series – Organic compounds – Carbohydrates or derivatives
Reexamination Certificate
2005-04-19
2010-10-12
Olson, Eric S (Department: 1623)
Organic compounds -- part of the class 532-570 series
Organic compounds
Carbohydrates or derivatives
C514S023000, C514S024000, C514S025000, C536S004100, C536S017200, C536S017500, C536S018300, C536S018700, C536S054000
Reexamination Certificate
active
07812142
ABSTRACT:
The present invention relates to pentose and pentose derivatives that are effective at increasing glucose transport in a non-insulin dependent manner, and to uses thereof for a) treating and/or preventing hyperglycemia; b) treating and/or preventing the complications of hyperglycemia; c) treating diabetes; d) increasing the rate of cellular glucose transport; e) increasing the rate of cellular glucose uptake; f) improving the ability of a subject to metabolize glucose; g) treating daily blood glucose fluctuations; h) reducing blood sugar levels; i) reducing the dosage of anti-diabetic medication needed for treatment of diabetes. The present invention further provides novel pentose derivatives having beneficial properties in terms of pharmacokinetics, to pharmaceutical compositions comprising these novel compounds and uses thereof.
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Cerasi Erol
Gruzman Arie
Katzhendler Joshua
Sasson Shlomo
Hadasit Medical Research Services and Development Ltd.
Olson Eric S
Winston & Strawn LLP
Yissum Research Development Company of the Hebrew University of
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