Organic compounds -- part of the class 532-570 series – Organic compounds – Carbohydrates or derivatives
Patent
1988-07-12
1989-06-20
Griffin, Ronald W.
Organic compounds -- part of the class 532-570 series
Organic compounds
Carbohydrates or derivatives
536121, 536123, C08B 3700, A61K 31715
Patent
active
048410411
ABSTRACT:
The present invention is dealing with new pentasaccharides of the formula I: ##STR1## These pentasaccharides have anti-thrombotic activity and especially they possess potent anti-Xa activity, inactivate thrombin via HC-II, but do not inactivate thrombin via AT-III.
The invention also refers to new tetrasaccharides which may be used as intermediates in the synthesis of the above pentasaccharides.
REFERENCES:
patent: 4777161 (1988-10-01), Lormeau et al.
Beetz Tom
Petitou Maurice
van Boeckel Constant A. A.
Akzo N.V.
Blackstone William M.
Griffin Ronald W.
Sanofi (S.A.)
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