Pentanedioic acid derivatives

Details Pentanedioic acid derivatives Pentanedioic acid derivatives

1985-10-10

1987-02-24

Trousof, Natalie

Organic compounds -- part of the class 532-570 series

Organic compounds

Carboxylic acids and salts thereof

562470, 562508, 562509, C07C 59245

Patent

active

046458581

ABSTRACT:
Compounds of formula I are described which are useful to inhibit the formation of serum cholesterol by virtue of their ability to inhibit .beta.-hydroxy-.beta.-methylglutaryl-CoA(HMG CoA), the rate-controlling substance in the synthesis of serum cholesterol.

REFERENCES:
patent: 3818080 (1974-06-01), Baran et al.
patent: 4554359 (1985-11-01), Lowrie et al.

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