Pentaerythritol lipid derivatives and nucleic-acid complexes

Details Pentaerythritol lipid derivatives and nucleic-acid complexes Pentaerythritol lipid derivatives and nucleic-acid complexes

1998-04-03

2000-03-28

Higel, Floyd D.

Organic compounds -- part of the class 532-570 series

Organic compounds

Carboxylic acid esters

560171, 560224, 560156, C07C22904, C07C22924, C07C22926

Patent

active

060433906

ABSTRACT:
This invention relates to pentaerythritol lipid derivatives which are useful for the intracellular delivery of polynucleotides. These cationic lipids are useful in the preparation of liposomes and other lipid vesicles for the delivery of nucleic acids into mammalian cells.

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