Pentadeuterioretinoids

Details Pentadeuterioretinoids Pentadeuterioretinoids

1982-09-09

1985-07-16

Trousof, Natalie

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Ester doai

260404, 2604055, 2604105, 2604109V, 514557, 514613, 514859, 514861, 514863, A61K 31215, C07C 69608, C07C10300, C07C10330

Patent

active

045296006

ABSTRACT:
Retinoic acid-4,4,18,18,18-d.sub.5 and esters and amides thereof are disclosed. These compounds are useful as chemopreventive agents for inhibiting tumor promotion in epithelial cells and for treating nonmalignant skin disorders.

REFERENCES:
patent: 3781314 (1973-12-01), Bollag et al.
patent: 4129662 (1978-12-01), Gander et al.
patent: 4190594 (1980-02-01), Gander et al.
patent: 4193931 (1980-03-01), Loeliger
patent: 4216224 (1980-08-01), Yu et al.
Verma et al., Cancer Research, 39, pp. 419-425, Feb. 1979.
Bouthwell et al., Advances in Enzyme Regulation, vol. 17, pp. 89-112, Pergamon Press Oxford and New York, 1979.
Dawson et al., I, J. Med. Chem., 23, pp. 1013-1022, Sep. 1980.
Dawson et al., II, J. Med. Chem., 24, pp. 583-592, May 1981.
Dawson et al., III, J. Med. Chem., 24, pp. 1214-1223, Oct. 1981.

Affiliated with

Also associated with

Rating

Pentadeuterioretinoids does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Pentadeuterioretinoids, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Pentadeuterioretinoids will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-1735630