Pentacyclic triterpenoid compounds as topoisomerase inhibitors o

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Heterocyclic carbon compounds containing a hetero ring...

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4241951, A61K 3143, A01N 6300

Patent

active

050648233

ABSTRACT:
Pentacyclic triterpenoid compounds such as .alpha. boswelic acid and its acetate, .beta.-boswellic acid and its acetate, which have an inhibitory effect on topoisomerase I and topoisomerase II, are disclosed. Compositions based on the pentacyclic triterpenoid compounds which can be used to treat various cancers in mammals are also disclosed.

REFERENCES:
patent: 4501734 (1985-02-01), Tanaka et al.

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