Pentacyclic compounds, their pharmaceutical compositions, and me

Details Pentacyclic compounds, their pharmaceutical compositions, and me Pentacyclic compounds, their pharmaceutical compositions, and me

1983-03-25

1984-09-04

Bond, Robert T.

Drug, bio-affecting and body treating compositions

Antigen, epitope, or other immunospecific immunoeffector

Bacterium or component thereof or substance produced by said...

2602393P, 2602433, 2602444, 544342, A61K 3155, C07D48714

Patent

active

044696973

ABSTRACT:
Compounds of formula (I), and pharmaceutically acceptable salts thereof: ##STR1## wherein: X is CH.sub.2, O, S or NR.sub.4 wherein R.sub.4 is hydrogen or C.sub.1-4 alkyl;

REFERENCES:
patent: 3354041 (1970-10-01), Van der Burg et al.
patent: 3701778 (1972-10-01), Van der Burg
S. Ogren et al., "Reevaluation of the Indoleamine Hypothesis of Depression. Evidence for a Reduction of Functional Activity of Central 5-HT Systems by Antidepressant Drugs," J. Neural. Trans., 46, pp. 85-103, (1979).
L. Stein et al., "Effects of Benzodiazepines on Cental Serotonergic Mechanisms," Advances in Biochemical Psychopharmacology, vol. 14, pp. 29-44, (Raven Press, New York City, 1975).

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