Penicillins having an imino substituted piperazindioncarbonylami

Drug – bio-affecting and body treating compositions – Antigen – epitope – or other immunospecific immunoeffector – Bacterium or component thereof or substance produced by said...

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Details

424271, 2602391, A61K 3143, C07D49964, C07D49966, C07D49968

Patent

active

041894820

ABSTRACT:
Penicillins of the formula ##STR1## wherein R is hydrogen , sodium, potassium or certain ester groups; R.sub.1 is in the .alpha.-configuration and is hydrogen or methoxy; R.sub.2 is hydrogen, lower aklkyl, cycloalkyl, cycloalkenyl, cycloalkadienyl, substituted or unsubstituted phenyl, benzyl, phenethyl, thienyl, furyl, or pyridyl, or 2-amino-4-thiazolyl; R.sub.3 is lower alkyl or substituted or unsubstituted phenyl, benzyl, phenethyl, thienyl or furyl; and R.sub.4 is hydrogen or lower alkyl; are disclosed. These compounds possess useful antibacterial activity.

REFERENCES:
patent: 4087424 (1978-05-01), Saikawa et al.

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