Penicillins having an imino substituted piperazindioncarbonylami

Details Penicillins having an imino substituted piperazindioncarbonylami Penicillins having an imino substituted piperazindioncarbonylami

1978-10-12

1980-02-19

Schwartz, Gerald A.

Drug, bio-affecting and body treating compositions

Antigen, epitope, or other immunospecific immunoeffector

Bacterium or component thereof or substance produced by said...

424271, 2602391, A61K 3143, C07D49964, C07D49966, C07D49968

Patent

active

041894820

ABSTRACT:
Penicillins of the formula ##STR1## wherein R is hydrogen , sodium, potassium or certain ester groups; R.sub.1 is in the .alpha.-configuration and is hydrogen or methoxy; R.sub.2 is hydrogen, lower aklkyl, cycloalkyl, cycloalkenyl, cycloalkadienyl, substituted or unsubstituted phenyl, benzyl, phenethyl, thienyl, furyl, or pyridyl, or 2-amino-4-thiazolyl; R.sub.3 is lower alkyl or substituted or unsubstituted phenyl, benzyl, phenethyl, thienyl or furyl; and R.sub.4 is hydrogen or lower alkyl; are disclosed. These compounds possess useful antibacterial activity.

REFERENCES:
patent: 4087424 (1978-05-01), Saikawa et al.

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