Penicillins and processes for their preparation and use

Details Penicillins and processes for their preparation and use Penicillins and processes for their preparation and use

1976-06-04

1977-06-21

Schwartz, Gerald A.

Drug, bio-affecting and body treating compositions

Antigen, epitope, or other immunospecific immunoeffector

Parasitic organism or component thereof or substance...

2602391, A61K 3143, C07D49966, C07D49968, C07D49970

Patent

active

040312291

ABSTRACT:
6-[.alpha.-(Imidazolidin-2-on-1-carbonylamido)acetamido]-penicillanic acids substituted in the 3-position of the imidazolidinone ring with phenyl or a substituted phenyl group and on the .alpha.-carbon atom of the acetamido bridge with a phenyl, thienyl, cyclohexenyl or cyclohexadienyl group, and their salts, are antibacterial agents. The compounds, of which .alpha.-(3-phenylimidazolidin-2-on-1-ylcarbonylamino)benzylpenicillin is a representative example, are prepared by acylation of the corresponding 6-(.alpha.-aminoacetamido)penicillanic acid or a derivative thereof.

REFERENCES:
patent: 3959258 (1976-06-01), Konig et al.
patent: 3966709 (1976-06-01), Konig et al.
patent: 3972870 (1976-08-01), Konig et al.
patent: 3975375 (1976-08-01), Konig et al.

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