Penicillin derivatives

Details Penicillin derivatives Penicillin derivatives

1974-10-15

1976-02-17

Schwartz, Gerald A.

Chemistry of carbon compounds

Miscellaneous organic carbon compounds

C-metal

424271, C07D49968

Patent

active

039391507

ABSTRACT:
The penicillin derivatives represented by the formula ##SPC1##
Wherein ring A represents a 5- or 6-membered single or fused ring which may contain one or more nitrogen atoms, an oxygen atom, or a sulfur atom; R.sup.1, R.sup.2, and R.sup.3, which may be the same or different, each represents a hydrogen atom, a hydroxy group, a lower alkyl group, a nitro group, a halogen atom, or an oxo group; and B represents a p-hydroxyphenyl group or a 1,4-cyclohexadien -1-yl group, and their nontoxic pharmaceutically acceptable salts.
The compounds are antibiotics having excellent antibacterial activity in particular with respect to the Pseudomonas genus.

REFERENCES:
patent: 3268513 (1966-08-01), Grant et al.
patent: 3433784 (1969-03-01), Long et al.
patent: 3479339 (1969-11-01), Holdrege et al.

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