Drug – bio-affecting and body treating compositions – Antigen – epitope – or other immunospecific immunoeffector – Bacterium or component thereof or substance produced by said...
Patent
1978-01-06
1979-10-02
Ford, John M.
Drug, bio-affecting and body treating compositions
Antigen, epitope, or other immunospecific immunoeffector
Bacterium or component thereof or substance produced by said...
544 54, 2603473, 26032643, 546233, 560 16, 560153, 562557, 424309, 424311, 424317, 542416, 544400, 544160, 546331, 549 76, 549 60, 549 77, A61K 3154, C07D27906
Patent
active
041698991
ABSTRACT:
Penicillamine compounds of the formula: ##STR1## and of the formula: ##STR2## wherein R.sup.1, R.sup.2, R.sup.3, A and B are as defined hereinafter, and pharmaceutically acceptable acid addition salts thereof are disclosed. II are the products of hydrolysis or alcoholysis of I, and I are in turn the products of dehydration of II or alcohol removal form II. I and II are useful for the treatment of rheumatoid arthritis.
REFERENCES:
patent: 2585064 (1952-02-01), Wheeler et al.
patent: 3732216 (1973-05-01), Weinstock
Cherbuliez et al., Helvetica Chemica Acta., vol. 48, pp. 1414-1423 (1965).
Campaigne et al., Jour. Medicinal Chemistry, vol. 7, pp. 132-135 (1965).
Goto Kazuhiro
Maruyama Yutaka
Shiroki Masami
Fan Jane T.
Ford John M.
Yoshitomi Pharmaceutical Industries Ltd.
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