Drug – bio-affecting and body treating compositions – Radionuclide or intended radionuclide containing; adjuvant... – In an organic compound
Reexamination Certificate
2007-02-20
2007-02-20
Jones, Dameron L. (Department: 1618)
Drug, bio-affecting and body treating compositions
Radionuclide or intended radionuclide containing; adjuvant...
In an organic compound
C424S001110, C424S009100, C534S014000
Reexamination Certificate
active
10405094
ABSTRACT:
The disclosure provides pendant fatty acid compounds for use in diagnostic imaging, (particularly the cardiovascular system), as well as kits comprised of the same. The disclosure also provides for a method administering a imaging agent with a high specificity for the myocardium.
REFERENCES:
patent: 4524059 (1985-06-01), Elmaleh et al.
patent: 4615876 (1986-10-01), Troutner et al.
patent: 4746505 (1988-05-01), Jones et al.
patent: 6437103 (2002-08-01), Babich et al.
patent: 1 046 401 (2000-10-01), None
patent: WO 97/19705 (1997-06-01), None
patent: WO 00/61196 (2000-10-01), None
Alberto et al.; “A Novel Organometallic Aqua Complex of Technetium for the Labeling of Biomolecules: Synthesis of [99mTc(OH2)3(CO)3]+from [99mTcO4]- In Aqueous Solution and Its Reaction with a Bifuctional Ligand”, J. Am. Chem. Soc. 120: 7987-7988, (1988).
Goodman et al.; “Synthesis and Evaluation of Radioiodinated Terminal p-Iodophenyl-Substituted α- and β-Methyl-Branched Fatty Acids”, J. Med. Chem. 27: 390-397, (1984).
Jones et al.; “7,10 Bis (2-Mercapto-2-Methyl) Propyl-7,10-Diazapalmitic Acid: A Novel, N2S2Ligand for Technetium-99m”, Bioorganic & Medicinal Chemistry Letters, 6(20): 2399-2404, (1996).
Lee, et al.; “Synthesis and Evaluation of Cyclopentadienyl Tricarbonyl99mTc Hexadecanoic Acid For Myocardial Imaging”, Journal of Nuclear Medecine, 42(5): 260P, (May 2001).
Lee et al.; “Cyclopentadienyl Tricarbonyl Technetium-99m Octanoic Acid: A Novel Radiotracer for Evaluation of Fatty Acid Metabolism in the Liver”, J. Labelled Cpd Radiopharm. 44 (suppl.1): S535—S535, (2001).
Magata et al.; “99mTc- Labeled Long Chain Fatty Acid Derivative for Myocardial Imaging”, Journal of Nuclear Medicine, 42(5): Suppl. P. 260P (May 2001).
Rattat et al.; “Dicarbonyl-Nitrosyl-Complexes of Rhenium (Re) and Technetium (Tc), A Potentially New Class of Compounds for the Direct Radiolabeling of Biomolecules”, Cancer Biotherapy & Radiopharmaceuticals, 16(4):339-343, (Nov. 4, 2001).
Yamamura et al.; “Technetium-99m-Labeled Medium Chain Fatty Acid Analogues Metabolized by β-Oxidation: Radiopharmaceutical for Assessing Liver Function”, Bioconjugate Chem. 10: 489-495, (1999).
International Search Report Completed on Jul. 18, 2003 and Mailed on Aug. 5, 2003.
Ewing James F.
Foley & Lardner LLP
Jones Dameron L.
Molecular Insight Pharmaceuticals, Inc.
Morency Michel
LandOfFree
Pendant fatty acid imaging agents does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Pendant fatty acid imaging agents, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Pendant fatty acid imaging agents will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-3864296