Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Heterocyclic carbon compounds containing a hetero ring...
Patent
1986-12-10
1988-07-26
Rizzo, Nicholas S.
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Heterocyclic carbon compounds containing a hetero ring...
540310, 514195, C07D49900, A61K 31425
Patent
active
047600586
ABSTRACT:
Described is a novel process for the preparation of penams and penems useful as antibacterial agents, which comprises the reaction of an appropriate f-substituted-azetidin-2-one with a base, followed by reaction of the thereby formed penam compound with an oxidating agent and an organic or inorganic base.
Also described are novel pemam compounds useful as antibacterials which are prepared by the described process.
REFERENCES:
patent: 4340539 (1982-07-01), Gottstein
patent: 4356174 (1982-10-01), Barth
patent: 4528135 (1985-07-01), Henniger et al.
Bedeschi Angelo
Hanessian Stephen
Farmitalia Carlo Erba S.p.A.
Rizzo Nicholas S.
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