PEG-LHRH analog conjugates

Chemistry: natural resins or derivatives; peptides or proteins; – Peptides of 3 to 100 amino acid residues – Lutenizing hormone releasing factor ; related peptides

Reexamination Certificate

Rate now

  [ 0.00 ] – not rated yet Voters 0   Comments 0

Details

C530S328000, C530S334000, C530S338000, C530S344000, C424S009100, C424S185100, C514S002600, C514S506000

Reexamination Certificate

active

11135475

ABSTRACT:
PEG-LHRH analog conjugates, where a PEG moiety is covalently bound to a serine residue of a LHRH analog, and methods for producing these conjugates are provided in the present invention. Also provided are a pharmaceutical composition and a method for treating pathologies in which LHRH analog administration is beneficial.

REFERENCES:
patent: 5840900 (1998-11-01), Greenwald et al.
patent: 6914121 (2005-07-01), El-Tayar et al.
patent: 0 377 665 (1995-07-01), None
patent: WO9404193 (1994-03-01), None
patent: WO9427641 (1994-12-01), None
patent: WO9621469 (1996-07-01), None
Felix et al., “Site-Specific Poly(ethylene glycol)ylation of Peptides”,American Chemical Society, symposium series 218-219 (1997).
XP-002114783 ABSTRAST—“Peptide(s) modified with polyethylene glycol—e.g. calcitonin GRP, elastase, etc. have prolonged activity” (1991).
XP-002065823 Zalipsky—“Functionalized Poly(ethylene glycol) for Preparation of Biologically Relevant Conjugates”,Bioconjugate Chem.,6:510-165 (1995).
Karten M.J. et al.,Endocrine Reviews, 7(1)44-66 (1986).
Nicholson et al.,Cancer Treat. Res.,39:1-23 (1988).
Kolb V. M.,Prog. Drug.,42:39-52 (1992).
Klijn J.G.M.,Recent Results Cancer Res.,124:75-90 (1992).
Emoons G. et al.,Recent Results Cancer Res.,124:55-68 (1992).
El-Roeiy A. et al.,Curr. Oin. Obstet. Gynecol.,2(2)166-172 (1990).

LandOfFree

Say what you really think

Search LandOfFree.com for the USA inventors and patents. Rate them and share your experience with other people.

Rating

PEG-LHRH analog conjugates does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with PEG-LHRH analog conjugates, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and PEG-LHRH analog conjugates will most certainly appreciate the feedback.

Rate now

     

Profile ID: LFUS-PAI-O-3767568

  Search
All data on this website is collected from public sources. Our data reflects the most accurate information available at the time of publication.