Peak selection in multidimensional data

Details Peak selection in multidimensional data Peak selection in multidimensional data

2007-03-27

2007-03-27

Wachsman, Hal (Department: 2857)

Data processing: measuring, calibrating, or testing

Measurement system in a specific environment

Chemical analysis

C702S030000, C702S027000, C702S032000, C250S282000

Reexamination Certificate

active

11075370

ABSTRACT:
An automatic peak selection method for multidimensional data that selects peaks from very noisy data such as two-dimensional liquid chromatography-mass spectrometry (LC-MS) data is described. Such data are characterized by non-normally distributed noise that varies in different dimensions. The method computes local noise thresholds for each one-dimensional component of the data. Each point has a local noise threshold applied to it for each dimension of the data set, and a point is selected as a candidate peak only if its value exceeds all of the applied local noise thresholds. Contiguous candidate peaks are clustered into actual peaks. The method is preferably implemented as part of a high-throughput platform for analyzing complex biological mixtures.

REFERENCES:
patent: 3552865 (1971-01-01), Leung et al.
patent: 3690836 (1972-09-01), Buissiere et al.
patent: 3997298 (1976-12-01), McLafferty et al.
patent: 3999047 (1976-12-01), Green
patent: 4405235 (1983-09-01), Rossiter
patent: 4426451 (1984-01-01), Columbus
patent: 4643570 (1987-02-01), Machler et al.
patent: 4752888 (1988-06-01), Yoshihara
patent: 4761381 (1988-08-01), Blatt et al.
patent: 4786813 (1988-11-01), Svanberg et al.
patent: 4844617 (1989-07-01), Kelderman et al.
patent: 4963498 (1990-10-01), Hillman et al.
patent: 5072382 (1991-12-01), Kamentsky
patent: 5091652 (1992-02-01), Mathies et al.
patent: 5119315 (1992-06-01), Kemp et al.
patent: 5127730 (1992-07-01), Brelje et al.
patent: 5192980 (1993-03-01), Dixon et al.
patent: 5239178 (1993-08-01), Derndinger et al.
patent: 5274240 (1993-12-01), Mathies et al.
patent: 5304810 (1994-04-01), Amos
patent: 5377003 (1994-12-01), Lewis et al.
patent: 5412208 (1995-05-01), Covey et al.
patent: 5430542 (1995-07-01), Shepherd
patent: 5446532 (1995-08-01), Yamazaki
patent: 5453505 (1995-09-01), Lee et al.
patent: 5456252 (1995-10-01), Vari et al.
patent: D366938 (1996-02-01), Shartle et al.
patent: 5492833 (1996-02-01), Rodriguez et al.
patent: 5523573 (1996-06-01), Hanninen et al.
patent: 5532873 (1996-07-01), Dixon
patent: 5547849 (1996-08-01), Baer et al.
patent: 5556764 (1996-09-01), Sizto et al.
patent: 5578832 (1996-11-01), Trulson et al.
patent: 5585246 (1996-12-01), Dubrow et al.
patent: 5592402 (1997-01-01), Beebe et al.
patent: 5627041 (1997-05-01), Shartle
patent: D382648 (1997-08-01), Shartle et al.
patent: 5658735 (1997-08-01), Lee
patent: D383852 (1997-09-01), Shartle et al.
patent: 5672869 (1997-09-01), Windig et al.
patent: 5682038 (1997-10-01), Hoffman
patent: 5687964 (1997-11-01), Stephan et al.
patent: 5689110 (1997-11-01), Dietz et al.
patent: 5692220 (1997-11-01), Diamond et al.
patent: 5710713 (1998-01-01), Wright et al.
patent: D391373 (1998-02-01), Shartle
patent: 5713364 (1998-02-01), DeBaryshe et al.
patent: 5726751 (1998-03-01), Altendorf et al.
patent: 5734058 (1998-03-01), Lee
patent: 5736410 (1998-04-01), Zarling et al.
patent: 5739000 (1998-04-01), Bierre et al.
patent: 5741411 (1998-04-01), Yeung et al.
patent: D395708 (1998-06-01), Shartle
patent: 5795729 (1998-08-01), Lee
patent: 5814820 (1998-09-01), Dong et al.
patent: 5832826 (1998-11-01), Mack et al.
patent: 5867610 (1999-02-01), Lee et al.
patent: 5871946 (1999-02-01), Lucas et al.
patent: 5885841 (1999-03-01), Higgs, Jr. et al.
patent: 5910287 (1999-06-01), Cassin et al.
patent: 5912134 (1999-06-01), Shartle
patent: 5932428 (1999-08-01), Dubrow et al.
patent: 5962238 (1999-10-01), Sizto et al.
patent: 5981180 (1999-11-01), Chandler et al.
patent: 5995989 (1999-11-01), Gedcke et al.
patent: 6002986 (1999-12-01), Mito
patent: 6008490 (1999-12-01), Kato
patent: 6008896 (1999-12-01), Sabsabi et al.
patent: 6017693 (2000-01-01), Yates et al.
patent: 6059724 (2000-05-01), Campbell
patent: 6063338 (2000-05-01), Pham et al.
patent: 6066216 (2000-05-01), Ruppel, Jr.
patent: 6072624 (2000-06-01), Dixon et al.
patent: 6091492 (2000-07-01), Strickland et al.
patent: 6093573 (2000-07-01), Beamer et al.
patent: 6104945 (2000-08-01), Modell et al.
patent: 6112161 (2000-08-01), Dryden et al.
patent: 6133046 (2000-10-01), Clerc
patent: 6134002 (2000-10-01), Stimson et al.
patent: 6138117 (2000-10-01), Bayardo
patent: 6147344 (2000-11-01), Annis et al.
patent: 6200532 (2001-03-01), Wu et al.
patent: 6207955 (2001-03-01), Wells et al.
patent: 6215892 (2001-04-01), Douglass et al.
patent: 6229603 (2001-05-01), Coassin et al.
patent: 6229635 (2001-05-01), Wulf
patent: 6232114 (2001-05-01), Coassin et al.
patent: 6236945 (2001-05-01), Simpson et al.
patent: 6253162 (2001-06-01), Jarman et al.
patent: 6278794 (2001-08-01), Parekh et al.
patent: 6334099 (2001-12-01), Grace et al.
patent: 6376843 (2002-04-01), Palo
patent: 6377842 (2002-04-01), Pogue et al.
patent: 6388788 (2002-05-01), Harris et al.
patent: 6391649 (2002-05-01), Chait et al.
patent: 6400487 (2002-06-01), Harris et al.
patent: 6421612 (2002-07-01), Agrafiotis et al.
patent: 6449584 (2002-09-01), Bertrand et al.
patent: 6514767 (2003-02-01), Natan
patent: 6526299 (2003-02-01), Pickard
patent: 6552784 (2003-04-01), Dietz et al.
patent: 6590204 (2003-07-01), Baranov
patent: 6603537 (2003-08-01), Dietz et al.
patent: 6620591 (2003-09-01), Dunlay et al.
patent: 6625546 (2003-09-01), Sepetov et al.
patent: 6642059 (2003-11-01), Chait et al.
patent: 6646271 (2003-11-01), Yokokawa et al.
patent: 6687395 (2004-02-01), Dietz et al.
patent: 6753966 (2004-06-01), Von Rosenberg
patent: 6787761 (2004-09-01), Hastings
patent: 6800860 (2004-10-01), Dietz et al.
patent: 6835927 (2004-12-01), Becker et al.
patent: 6858435 (2005-02-01), Chervet et al.
patent: 6873915 (2005-03-01), Hastings
patent: 6937330 (2005-08-01), Dietz et al.
patent: 6950185 (2005-09-01), Da Silva et al.
patent: 6962818 (2005-11-01), Schneider et al.
patent: 6979830 (2005-12-01), Dietz et al.
patent: 2001/0019829 (2001-09-01), Nelson et al.
patent: 2002/0049152 (2002-04-01), Nock et al.
patent: 2002/0053545 (2002-05-01), Greef
patent: 2002/0095419 (2002-07-01), Parce
patent: 2002/0102610 (2002-08-01), Townsend et al.
patent: 2002/0123055 (2002-09-01), Estell et al.
patent: 2002/0141051 (2002-10-01), Vogt et al.
patent: 2003/0087322 (2003-05-01), Aebersold et al.
patent: 2004/0257576 (2004-12-01), Kirsch et al.
patent: 2006/0000984 (2006-01-01), Wolleschensky et al.
patent: 0296136 (1988-12-01), None
patent: 0421736 (1991-04-01), None
patent: 0681177 (1995-11-01), None
patent: 0969283 (2000-01-01), None
patent: 1407247 (1975-09-01), None
patent: WO-97 43732 (1997-11-01), None
patent: WO 98/1661 (1998-04-01), None
patent: WO 00/67017 (2000-11-01), None
patent: WO-00 70340 (2000-11-01), None
patent: WO 01/35266 (2001-05-01), None
patent: WO-01 44269 (2001-06-01), None
patent: WO-2088819 (2002-11-01), None
Gygi et al. (1999) Nat. Biotech. 17:994-999, no month.
do Lago et al. (1995) Anal. Chim. Acta, 310: 281-288, no month.
Windig et al. (1996) Anal. Chem., 68: 3602-3606, no month.
Schoonjans et al. (2000) J. Pharm. & Biomed. Analysis 21:1197-1214, no month.
Fiehn et al. (2000) Nat. Biotech. 18:1157-1161.
Chelius et al. (2002) J. Proteome Res. 1:317-323, no month.
Bryant et al. (2001) Rapid Commun. Mass Spectrom. 15:418-427, no month.
Wang et al. (1987) Analytical Chemistry 59:649-654, no month.
Aach & Church (2001) Bioinformatics 17:495-508, no month.
Nielsen et al, (1998) J. of Chromatography A. 805:17-35, no month.
Bylund et al. (2002) J. of Chromatography A. 961-237-244, no month.
Pravdova et al. (2002) Analytica Chimica Acta 456:77-92, no month.
Kassidas et al. (1998) AlChE Journal 44(4):864-875, no month.
Grung & Kvalheim (1995) Analytica Chimica Acta 304:57-66, no month.
Prazen et al. (Jan. 15, 1998) Anal. Chem. 70:218-225, no month.
Sakoe & Chiba (2002) IEEE Transactions on Acoustic, Speech and Signal Processing ASSP26(1):43-49.
Breen et al. (2000) Electrophoresis 21:2243-2251, no month.
Koradi et al. (1998) J. Magn. Reson., 135:288-297, no month.
Stein (1999) J Am Soc Mass Spectrum 10:770-781, no month.
Hastings et al. (2002) Rapid Communications in Mass Spectrometry 16(5):462-465,467, no month.
Baumgarth et al., 2000, “A Practical Approach to Multicolor Flo

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