Chemistry: natural resins or derivatives; peptides or proteins; – Peptides of 3 to 100 amino acid residues
Patent
1998-11-04
2000-09-19
Duffy, Patricia A.
Chemistry: natural resins or derivatives; peptides or proteins;
Peptides of 3 to 100 amino acid residues
530350, 435 693, 435 697, 435183, 514 2, 514 12, A61K 3800, C07K 1400
Patent
active
061214140
ABSTRACT:
The invention provides pcrA polypeptides and DNA (RNA) encoding pcrA polypeptides and methods for producing such polypeptides by recombinant techniques. Also provided are methods for utilizing pcrA polypeptides to screen for antibacterial compounds.
REFERENCES:
Iordanescu, S., "Characterization of the Staphylococcus aurcus chromosomal gene pcrA, identified by mutations affecting plasmid pT181 replication" Mol Gen Genet (1993) 241: 185-192.
Iordanescu, S. and Bargonetti, J., "Staphylococcus aureus Chromosomal Mutations That Decrease Efficiency of Rep Utilization in Replication of pT181 and Related Plasmids" Journal of Bacteriology, Aug. 1989, p. 4501-4503.
Iordanescu, S. and Bargonetti, J., GenBank Submission, Accession No. M63176, 1994.
Black Michael Terence
Hodgson John Edward
Holmes David J
Knowles David Justin Charles
Lonetto Michael Arthur
Deibert Thomas S.
Duffy Patricia A.
Gimmi Edward R.
King William T.
SmithKline Beecham Corporation
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