Pax6 and Pax4 nucleic acid mixtures

Details Pax6 and Pax4 nucleic acid mixtures Pax6 and Pax4 nucleic acid mixtures

1996-12-31

2000-02-22

Fredman, Jeffrey

Organic compounds -- part of the class 532-570 series

Organic compounds

Carbohydrates or derivatives

536 243, 435 6, 4352402, 4353201, 514 44, C07H 2102, C07H 2104, C12N 510, C12N 1570

Patent

active

060281847

ABSTRACT:
The present invention relates to a novel method for testing the developmel status in pancreatic cells of a mammal. The present invention further relates to applications in the medical field that directly arise from the method of the invention. Additionally, the present invention relates to transgenic mammals comprising at least one inactivated Pax6 allele and optionally at least one inactivated Pax4 allele.

REFERENCES:
Walther et al. Development 113:1435-1450, 1991.
Correll et al. Human Gene Therapy 1: 277-287, 1990.
Paillard, Human Gene Therapy 8:2009-2010, 1997.
Orkin, Report and Recommendations of the Panel to Assess the NIH Investment in Research on Gene Therapy, 1995.

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