Patterning antibodies on a surface

Details Patterning antibodies on a surface Patterning antibodies on a surface

1997-03-13

1999-01-12

Chin, Christopher L.

Chemistry: analytical and immunological testing

Involving an insoluble carrier for immobilizing immunochemicals

430302, 430304, 430298, 430297, 430299, 422 57, 422 60, 435 33, 4352878, 4352879, 435973, 436527, 427 211, 427 213, 427466, 427470, 427504, 427534, 427288, 427286, C08J 704, G01N 33543

Patent

active

058588019

ABSTRACT:
A patterned multiple antibody substrate for use in biosensors or immunosensors is produced by (1) coating an antibody-adsorbent substrate with a material that resists antibody adsorption, (2) using ion beam sputtering, laser ablation, or mechanical scribing to remove the coating at specific sites on the substrate, and then (3) adsorbing specific antibodies at the sites. The substrate is capable of detecting multiple chemical species simultaneously.

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