Drug – bio-affecting and body treating compositions – In vivo diagnosis or in vivo testing – Diagnostic or test agent produces in vivo fluorescence
Reexamination Certificate
2007-08-07
2007-08-07
Jones, Dameron L. (Department: 1618)
Drug, bio-affecting and body treating compositions
In vivo diagnosis or in vivo testing
Diagnostic or test agent produces in vivo fluorescence
C424S001110, C424S001650, C424S001490, C424S009100, C548S146000
Reexamination Certificate
active
10847256
ABSTRACT:
Novel tumor specific phototherapeutic and photodiagnostic agents are disclosed. The compounds consist of a carbocyanine dye for visualization, photosensitizer for photodynamic treatment, and tumor receptor-avid peptide for site-specific delivery of the probe and phototoxic agent to diseased tissues. A combination of these elements takes full advantage of the unique and efficient properties of each component for an effective patient care management.
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Achilefu Samuel
Bugaj Joseph E.
Dorshow Richard B.
Rajagopalan Raghavan
Jones Dameron L.
Mallinckrodt Inc.
Wood Herron & Evans LLP
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