Patched genes and their use

Details Patched genes and their use Patched genes and their use

1995-10-06

1998-11-17

Chambers, Jasemine C.

Chemistry: molecular biology and microbiology

Animal cell, per se ; composition thereof; process of...

536 231, 536 235, 536 2431, 4351723, 435 691, 4353201, 435 912, 424 9321, C12N 516, C12N 1511, C12N 1509

Patent

active

058375384

ABSTRACT:
Invertebrate and vertebrate patched genes are provided, including the mouse and human patched genes, as well as methods for isolation of related genes, where the genes may be of different species or in the same family. Having the ability to regulate the expression of the patched gene, allows for the elucidation of embryonic development, cellular regulation associated with signal transduction by the patched gene, the identification of agonist and antagonist to signal transduction, identification of ligands for binding to patched, isolation of the ligands, and assaying for levels of transcription and expression of the patched gene.

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