Chemistry: natural resins or derivatives; peptides or proteins; – Proteins – i.e. – more than 100 amino acid residues – Blood proteins or globulins – e.g. – proteoglycans – platelet...
Patent
1985-06-03
1986-11-18
Schain, Howard E.
Chemistry: natural resins or derivatives; peptides or proteins;
Proteins, i.e., more than 100 amino acid residues
Blood proteins or globulins, e.g., proteoglycans, platelet...
424101, 424 85, 514 8, 514 21, 530381, 530382, 530383, 530386, 530393, 530830, 435188, A61K 3516, A61K 3702, A61K 3706, C07K 328
Patent
active
046237178
ABSTRACT:
Compositions containing thermally sensitive, therapeutically active proteins are pasteurized without substantial loss of therapeutic activity by mixing the protein composition with a pasteurization-stabilizing amount of a sugar or reduced sugar and of an amino acid prior to pasteurization. Pasteurized compositions containing therapeutically active proteins, which have heretofore been unattainable, can be prepared by the method of the invention.
REFERENCES:
patent: 4061735 (1977-12-01), Funakoshi et al.
patent: 4137307 (1979-01-01), Funakoshi et al.
patent: 4279344 (1981-10-01), Schwinn
patent: 4440679 (1984-04-01), Fernandes et al.
Fernandes Peter M.
Lundblad John L.
Giblin James A.
Miles Laboratories Inc.
Schain Howard E.
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