Passive delivery system diluents mixing and delivery

Details Passive delivery system diluents mixing and delivery Passive delivery system diluents mixing and delivery

2007-11-13

2007-11-13

Sirmons, Kevin C. (Department: 3767)

Surgery

Means for introducing or removing material from body for...

Treating material introduced into or removed from body...

C604S082000

Reexamination Certificate

active

10866434

ABSTRACT:
A syringe system for the administration of lyophilized drugs includes a syringe barrel and a stopper and a needled guard each coupled with the syringe barrel. A reconstitution plunger is removably coupled with the stopper. A diluent is withdrawn from the syringe into a vial containing a lyophilized drug, and the diluent and drug are mixed to form a therapeutic agent. The reconstitution plunger is then replaced by an administration plunger. The length of the reconstitution plunger is greater than the length of the administration plunger in order to prevent activation of the needle guard during reconstitution. Alternatively, a single plunger system may be used in which the plunger can transition from an extended length during reconstitution to a shortened length during administration. During administration, a radial element of the plunger contacts latch members of the needle guard, whereupon the shield advances to an extended position covering the needle.

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Instructions for Use for Bio-Set Injection from Bio-Set Website, printed Jan. 14, 2003 (http://www.bio-set.com/htm/InstUseInj.htm).
Press Release from PRWeb Website entitled “Second Patent For Mixing Lyophilized (Freeze-Dried) Drugs In A Needle-Less Injector Awarded To Penject® Corporation,” printed Jan. 14, 2003 (http://www.prweb.com/printer.php?prid=31822).

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