Chemistry: molecular biology and microbiology – Vector – per se
Patent
1991-02-15
1999-05-18
Crouch, Deborah
Chemistry: molecular biology and microbiology
Vector, per se
4352351, 435325, 435455, C12N15/00;7/00;5/00
Patent
active
059050403
ABSTRACT:
Empty viral capsids, particularly animal parvoviral empty capsids, induce protective antibody response against the virus. The empty viral capsids are obtained by recombinant DNA techniques. Expression vectors are constructed containing structural genes encoding capsid proteins in self assembling form. Eukaryotic transfectants express self-assembled empty viral capsids which can be used to vaccinate against the virus or antigenically related species of the virus.
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Destree Antonia T.
Mazzara Gail P.
Panicali Dennis L.
Bronstein Sewall P.
Crouch Deborah
Eisenstein Ronald I.
Resnick David S.
Therion Biologics Corporation
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