Particulate support matrix for making a rapidly dissolving table

Details Particulate support matrix for making a rapidly dissolving table Particulate support matrix for making a rapidly dissolving table

1994-01-27

1997-01-21

Webman, Edward J.

Drug, bio-affecting and body treating compositions

Preparations characterized by special physical form

Matrices

424486, 424488, 424499, A61K 910, A61K 914, A61K 4742

Patent

active

055957617

ABSTRACT:
The present invention comprises a particulate support matrix for making a solid tablet form, and method for making such, which disintegrates or dissolves in a matter of just a few seconds once placed into the oral cavity. Thee particulate support matrix comprises a first polymeric component which may be a polypeptide, preferably a non-hydrolyzed gelatin, a second polymeric component which may be a different polypeptide which may be a hydrolyzed gelatin and a bulking agent. The porous particulate powder can serve as the tablet support matrix, to which a pharmaceutical, for example an antihistamine, decongestant, or antibiotic is added.

REFERENCES:
patent: 4013784 (1977-03-01), Speiser
patent: 4572832 (1986-02-01), Kigasawa et al.
patent: 5082667 (1992-01-01), Van Scoik
patent: 5178878 (1993-01-01), Wehling et al.
patent: 5215756 (1993-06-01), Gole et al.

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