Stock material or miscellaneous articles – Coated or structually defined flake – particle – cell – strand,... – Particulate matter
Patent
1976-03-19
1979-03-06
Lesmes, George F.
Stock material or miscellaneous articles
Coated or structually defined flake, particle, cell, strand,...
Particulate matter
428403, 526 23, 526 49, 528502, B32B 516, B32B 904
Patent
active
041432037
ABSTRACT:
Particles having a mean diameter from 0.1 to 50 micrometers and having a solid core of water-impermeable polyacrylonitrile and a partially hydrolyzed hydrophilic surface layer enclosing the core containing from 0.001 to 0.8 milliequivalents of carboxyl or carboxylate groups per dry gram, the surface layer amounting to 0.01 to 20% by weight of the particles, are useful as a solid phase insoluble support to which biospecific reagents such as antigens or antibodies can be coupled. Variants include supports in which N-hydroxysuccinimide or various spacer arms are coupled to the carboxyl or carboxylate groups.
REFERENCES:
patent: 2548853 (1948-10-01), Baker
patent: 2719144 (1955-09-01), Shearer et al.
patent: 2861059 (1958-11-01), Mowry et al.
patent: 3758449 (1973-09-01), Hoppe et al.
patent: 3948870 (1976-04-01), Stoy et al.
Desaulniers Charles W.
Doucette David E.
Rigopulos Peter N.
Amicon Corporation
Lesmes George F.
Varndell, Jr. R. Eugene
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