Particulate drug-containing products and method of manufacture

Details Particulate drug-containing products and method of manufacture Particulate drug-containing products and method of manufacture

2006-10-24

2006-10-24

Kishore, Gollamudi S. (Department: 1615)

Drug, bio-affecting and body treating compositions

Preparations characterized by special physical form

Particulate form

C424S499000, C424S043000, C424S045000, C424S400000, C514S002600, C514S003100

Reexamination Certificate

active

07125566

ABSTRACT:
Provided is a compressed anti-solvent technique for manufacture of drug-containing powders for pulmonary delivery. The drug is processed in a cosolvent system including two or more mutually soluble organic solvents. Also provided are powders manufacturable by the manufacture method, including powders of substantially pure drug and powders including a biocompatible polymer for pulmonary sustained drug release applications. Also provided are packaged products including drug-containing powder in a container that is receivable by and operable with a dry powder inhaler to produce an aerosol including dispersed drug-containing particles when the inhaler is actuated.

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