Particles containing mannitol suitable for tabletting into diagn

Details Particles containing mannitol suitable for tabletting into diagn Particles containing mannitol suitable for tabletting into diagn

1989-01-12

1991-04-23

Rosen, Sam

Chemistry: molecular biology and microbiology

Measuring or testing process involving enzymes or...

435 6, 435 14, 435 18, 435 26, 435 17, 435 11, 435 25, 436513, 436543, 436547, C12Q 100

Patent

active

050099949

ABSTRACT:
A completely water-soluble, solid, labile biochemical-containing diagnostic reagent is prepared without the need of a lyophilization step, by spraying, preferably by a fluidized bed process, an aqueous solution of labile biochemical, e.g., an enzyme, onto small particles, e.g., lower than 20 mesh, of an inert, completely water-soluble solid bulking agent, e.g., mannitol; drying the resultant labile biochemical-coated bulking agent to the desired dryness; and then forming resultant dried labile biochemical-coated bulking agent into a tablet suitable for a diagnostic test reagent, said tablet having a predetermined rate of dissolution.

REFERENCES:
patent: 3413198 (1968-11-01), Deutsch
patent: 3451935 (1969-06-01), Roald et al.
patent: 3527331 (1970-09-01), Deutsch
patent: 3539450 (1970-11-01), Deutsch
patent: 3687717 (1972-08-01), Philip
patent: 3687853 (1972-08-01), Natali et al.
patent: 3721725 (1973-03-01), Briggs et al.
patent: 4106991 (1978-08-01), Markussen et al.
patent: 4242219 (1980-12-01), Bogerman et al.
patent: 4428973 (1984-01-01), Horner et al.
patent: 4447527 (1984-05-01), Monte et al.
patent: 4478829 (1984-10-01), Landaburu et al.
patent: 4489026 (1984-12-01), Yalkowsky
patent: 4572897 (1986-02-01), Amotz et al.
patent: 4578876 (1986-04-01), Cartwright et al.
patent: 4689297 (1987-08-01), Good et al.
Efimova et al-Chem. Abst., vol. 99 (1983), 43464r.
Ray et al.-Chem. Abst., vol. 103 (1985), p. 85, 331b.

Affiliated with

Also associated with

Rating

Particles containing mannitol suitable for tabletting into diagn does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Particles containing mannitol suitable for tabletting into diagn, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Particles containing mannitol suitable for tabletting into diagn will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-1621018