Liquid purification or separation – Processes – Separating
Patent
1998-05-26
2000-06-06
Kim, John
Liquid purification or separation
Processes
Separating
210786, 210787, 210789, 210806, 435 2, 435372, 4353723, 494 5, 494 7, 494 36, 494 37, 494 45, B01D 2126, B04B 100, B04B 910, B04B 1102, C12N 100
Patent
active
060714220
ABSTRACT:
An apparatus and method are disclosed for filtering or separating particles. The apparatus has a centrifuge rotor rotatable about an axis of rotation. A fluid chamber rotates with the rotor. A substance is supplied to the inlet of the chamber. A saturated fluidized bed of first particles forms within the fluid chamber and obstructs flow of second particles through the chamber. Additive substances alter sedimentation velocity of the first particles to modify the filtration characteristics of the saturated fluidized bed.
REFERENCES:
patent: 2616619 (1952-11-01), MacLeod
patent: 3825175 (1974-07-01), Sartory
patent: 4091989 (1978-05-01), Schlutz
patent: 4187979 (1980-02-01), Cullis et al.
patent: 4268393 (1981-05-01), Persidsky et al.
patent: 4269718 (1981-05-01), Persidsky
patent: 4316576 (1982-02-01), Cullis et al.
patent: 4322298 (1982-03-01), Perisdsky
patent: 4350283 (1982-09-01), Leonian
patent: 4416654 (1983-11-01), Schoendorfer et al.
patent: 4425112 (1984-01-01), Ito
patent: 4464167 (1984-08-01), Schoendorfer et al.
patent: 4675117 (1987-06-01), Neumann et al.
patent: 4680025 (1987-07-01), Kruger et al.
patent: 4701267 (1987-10-01), Watanabe et al.
patent: 4708710 (1987-11-01), Dunn, Jr.
patent: 4708712 (1987-11-01), Mulzet
patent: 4798579 (1989-01-01), Penhasi
patent: 4808151 (1989-02-01), Dunn, Jr. et al.
patent: 4851126 (1989-07-01), Schoendorfer
patent: 4885137 (1989-12-01), Lork
patent: 4936820 (1990-06-01), Dennehey et al.
patent: 4936998 (1990-06-01), Nishimura et al.
patent: 4939081 (1990-07-01), Figdor et al.
patent: 4939087 (1990-07-01), Van Wie et al.
patent: 5078671 (1992-01-01), Dennehey et al.
patent: 5089146 (1992-02-01), Carmen et al.
patent: 5100564 (1992-03-01), Pall et al.
patent: 5213970 (1993-05-01), Lopez-Berestein et al.
patent: 5224921 (1993-07-01), Dennehey et al.
patent: 5229012 (1993-07-01), Pall et al.
patent: 5282982 (1994-02-01), Wells
patent: 5298171 (1994-03-01), Biesel
patent: 5316666 (1994-05-01), Brown et al.
patent: 5316667 (1994-05-01), Brown et al.
patent: 5360542 (1994-11-01), Williamson, IV et al.
patent: 5362291 (1994-11-01), Williamson, IV
patent: 5370802 (1994-12-01), Brown
patent: 5397479 (1995-03-01), Kass et al.
patent: 5409813 (1995-04-01), Schwartz
patent: 5501795 (1996-03-01), Pall et al.
patent: 5529691 (1996-06-01), Brown
patent: 5547591 (1996-08-01), Hagihara et al.
patent: 5549834 (1996-08-01), Brown
patent: 5580465 (1996-12-01), Pall et al.
patent: 5587070 (1996-12-01), Pall et al.
patent: 5607830 (1997-03-01), Biesel et al.
patent: 5614106 (1997-03-01), Payrat et al.
patent: 5622819 (1997-04-01), Herman
patent: 5641414 (1997-06-01), Brown
patent: 5641622 (1997-06-01), Lake et al.
patent: 5643786 (1997-07-01), Cohen et al.
patent: 5674173 (1997-10-01), Hlavinka et al.
patent: 5722926 (1998-03-01), Hlavinka et al.
patent: 5906570 (1999-05-01), Langley et al.
patent: 5913768 (1999-08-01), Langley et al.
patent: 5939319 (1999-08-01), Hlavinka et al.
patent: 5951877 (1999-09-01), Langley et al.
Maxim D. Persidsky et al., Separation of Platelet-rich Plasma by Modified Centrifugal Elutriation; Journal of Clinical Apheresis 1:18-24 (1982).
John F. Jemionek et al., Special Techniques for the Separation of Hemopoietic Cells, Current Methodology in Experimental Hematology, 1984, pp. 12-16.
J. Freedman et al., White Cell Depletion of Red Cell and Pooled Random-Donor Platelet Concentrates by Filtration and Residual Lymphocyte Subset Analysis, Transfusion, 1991, vol. 31, No. 5, pp. 433-440.
Nancy M. Heddle et al., The Role of the Plasma from Platelet Concentrates in Transfusion Reactions, The New England Journal of Medicine, vol. 331, No. 10, Sep. 8, 1994, pp. 625-628, 670 and 671.
A. Bruil et al., Asymmetric Membrane Filters for the Removal of Leukocytes From Blood, Journal of Biomed. Materials Research, vol. 25, 1459-1480, 1991.
Sunny Dzik, Leukodepletion Blood Filters: Filter Design and Mechanisms of Leukocyte Removal, Transfusion Medicine Reviews, vol. VII, No. 2, Apr. 1993, pp. 65-77.
Bernard J. Van Wie et al., The Effect of Hematocrit and Recycle on Cell Separations, Plasma Ther. Transfus. Technol. 1986; 7:373-388.
P.D. Drumheller et al., The Effects of RPM and Recycle on Separation Efficiency in a Clinical Blood Cell Centrifuge, Journal of Biomechanical Engineering, Nov. 1987, vol. 109, pp. 324-329.
R.J. Oxford et al., Monitoring and Automated Optimization of a Cell Centrifuge, IEEE/Eighth Annual Conference of the Engineering in Medicine and Biology Society, pp. 925-927 (Undated).
R.J. Oxford et al., Interface Dynamics in a Centrifugal Cell Separator, Transfusion, Nov.-Dec., 1988, vol. 28, Nov. 6, pp. 588-592.
A. Tulp et al., A Separation Chamber to Sort Cells and Cell Organelles by Weak Physical Forces, V.A. Sector-Shaped Chamber and Its Application to the Separation of Peripheral Blood Cells, Journal of Immunological Methods 69 (1984), pp. 281-295.
Robert J. Grabske, Separating Cell Populations by Elutriation, pp. 1-8 (Undated).
Carl G. Figdor et al., Theory and Practice of Centrifugal Elutriation (CE) Factors Influencing the Separation of Human Blood Cells, Cell Biophysics 5, 105-118 (1983).
P.E. Lindahl, On Counter Streaming Centrifugation in the Separation of Cells and Cell Fragments (1956), pp. 411-415.
C. Almici et al., Counterflow Centrifugal Elutriation: Present and Future, Bone Marrow Transplantation 1993, 12:105-108.
Richard J. Sanderson, Separation of Different Kinds of Nucleated Cells from Blood by Centrifugal Elutriation, Cell Separation Methods and Selected Applications, vol. 1, pp. 153-168 (1982).
P.C. Keng et al., Characterization of the Separation Properties of the Beckman Elutriator System, Cell Biophysics 3 (1981), pp. 41-56.
Biofil, Systems for Filtration of Haemocomponents (Undated).
Claes, F. Hogman, Leucocyte Depletion of Blood Components, 1994, pp. 1, 156-173.
A.S. Buchanan et al., Principle of a Counter-streaming Centrifuge for the Separation of Particles of Different Sizes, Nature, Apr. 24, 1948, pp. 648-649.
"Cost-Effectiveness of Leukocyte Depletion of Blood Components", Presented at the 1993 AABB Meeting Miami Beach, FL.
I. Sniecinski, Prevention of Immunologic and Infectious Complications of Transfusion by Leukocyte Depletion, Prevention of Complications of Transfusion Chapter 18; pp. 202-211 (Undated).
Benefits of Leukocyte Filtration for Red Cell and Platelet Blood Products, Transfusion Associated CMV (1994), pp. 1-18.
G. Stack et al., Cytokine Generation in Stored Platelet Concentrates, Transfusion, 1994; 34:20-25.
N. M. Heddle et al., A Prospective study to identify the risk factors associated with acute reactions to platelet and red cell transfusions; Transfusion, 1993; 33:794-797.
H. Brandwein et al., Asahi Sepacell PL10A Leukocyte Removal Filter:Efficiency with Random Donor Platelet Pools, PALL Technical Report (Undated).
J. Whitbread et al., Performance Evaluation of the Sepacell PL10A filter and Pall PXL 8 filter: Measurement of Leukocyte Residuals and Consistency, PALL Technical Report (Undated).
R. Brown et al., Evaluation of a new separation method utilizing plasma recirculation and autoelutriation, Transfusion, 1994; vol. 34, Supp.
Richard J. Sanderson et al., Design Principles for a Counterflow Centrifugation Cell Separation Chamber; Analytical Biochemistry 71, 615-622(1976).
Designed to Provide the Reliability and Performance to Harvest a High Yield Component Product, The Haemonetics V50 Apheresis System (Undated).
Haemonetics Mobile Collection System Owner's Operating and Maintenance Manual, 1991 pp. 3-2 through 3-7 and pp. 1-6.
E.A. Burgstaler et al., White Blood Cell Contamination of Apheresis Platelets Collected on the COBE Spectra, COBE Blood Component Technology (1992).
T.H. Price et al., Platelet Collection Using the COBE Spectra, COBE Blood Component Technology (1989).
Nancy Besso et al., Asahi Sepacell PL-10A Leukocyte Removal Filter: Effect of Post-Filtration Flush With Saline, PALL Technical Report (1991).
Harvey J. Brandwein et al., Asahi Sepacell PL-10A Leukocyte Removal Filter Description and Review of Claims, PALL Technical Report (1991).
"Lower is Better!", (fly
Corbin Frank
Hlavinka Dennis
Cobe Laboratories, Inc.
Kim John
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