Particle analyzer and methods for use thereof

Electricity: measuring and testing – Determining nonelectric properties by measuring electric... – Particle counting

Reexamination Certificate

Rate now

  [ 0.00 ] – not rated yet Voters 0   Comments 0

Details

Reexamination Certificate

active

10056103

ABSTRACT:
A quantitative microchip Coulter counter is provided for use in detecting and measuring particles or macromolecules. The device comprises a conduit, a fluid handling system, and a measurement system. Preferably, the conduit is at least in part formed from an elastomeric material.

REFERENCES:
patent: 3919050 (1975-11-01), Curby
patent: 3944917 (1976-03-01), Hogg et al.
patent: 3984307 (1976-10-01), Kamentsky et al.
patent: 4607526 (1986-08-01), Bachenheimer et al.
patent: 4810650 (1989-03-01), Kell et al.
patent: 5376878 (1994-12-01), Fisher
patent: 5744366 (1998-04-01), Kricka et al.
patent: 5824477 (1998-10-01), Stanley
patent: 6168948 (2001-01-01), Anderson et al.
patent: 6426615 (2002-07-01), Mehta
patent: WO94/02846 (1994-02-01), None
patent: WO 00/49385 (2000-08-01), None
patent: WO 01/18246 (2001-03-01), None
Duffy et al., “Rapid Prototyping of Microfluidic Systems in Poly(dimethylsiloxane)”, (1998) Analytical Chemistry, vol. 70, No. 23, pp. 4974-84.
DeBlois et al., “Counting and sizing of submicron particles by the resistive pulse technique”, (1970) Rev. Sci. Instrum., Database accession No. 194870, XP002215413, Abstract.
Communication relating to the results of the partial international search, PCT/US02/02144, mailed Nov. 15, 2002, EPO.
Koutsouris et al., “Determination of Erthrocyte Transit Times Through Micropores”, Biorheology, vol. 25, pp. 763-772, 1988.
Koch et al., “Two Simple Micromixers Based on Silicon”, J. Micromech. Microeng., pp. 123-126, 1988.
Tracey et al., “A Silicon Micromachined Device for Use in Blood Cell Deformability Studies”, IEEE Transactions on Biomedical Engineering, vol. 42, No. 8, pp. 751-761, Aug. 1995.
DeBlois et al., “Counting and Sizing of Submicron Particles by the Resistive Pulse Technique”, The Review of Scientific Instruments, vol. 41, No. 7, pp. 909-916, Jul. 1970.
Koch et al., “Design and Fabrication of a Micromachined Coulter Counter”, J. Micromech. Microeng., vol. 9, pp. 159-161, 1999.
DeBlois et al., “Electrokinetic Measurements with Submicron Particles and Pores by the Resistive Pulse Techniques”, Journal of Colloid and Interface Science, vol. 61, No. 2, pp. 323-335, Sep. 1977.
Asami et al., “Real-Time Monitoring of Yeast Cell Division by Dielectric Spectroscopy”, Biophysical Journal, vol. 76, pp. 3345-3348, Jun. 1999.
Chou et al., “A Microfabricated Device for Sizing and Sorting DNA Molecules”, Proc. Natl. Acad. Sci. USA, vol. 96, pp. 11-13, Jan. 1999.
Saleh et al., “Quantitative Sensing of Nanoscale Colloids using a Microchip Coulter Counter”, Review of Scientific Instruments, vol. 72, No. 12, pp. 4449-4451, Dec. 2001.
Saleh et al., “A Quantitative Nanoscale Coulter Counter”, Abstract for presentation at Oct. 2001 MicroTAS conference, in Monterey, CA, 3 pages.
Saleh et al., “A Quantitative Nanoscale Coulter Counter” Presentation at Oct. 2001 MicroTAS conference, in Monterey, CA, 17 pages.
Unger et al., “Monolithic Microfabricated Valves and Pumps by Multilayer Soft Lithography”, Science, vol. 288, pp. 113-116, Apr. 7, 2000.
Quake et al., “From Micro- to Nanofabrication with Soft Materials”, Science, vol. 290, pp. 1536-1540, Nov. 24, 2000.
Fu et al., “A Microfabricated Fluorescence-Activated Cell Sorter”, Nature Biotechnology, vol. 17, pp. 1109-1111, Nov. 1999.
Sun et al., “Fabrication and Characterization of Single Pores for Modeling Mass Transport across Porous Membranes”, Langmuir, vol. 15, pp. 738-741, 1999.
Larsen et al., “Microchip Coulter Particle Counter”, Transducers '97, pp. 1319-1322, 1997.
Fan et al., “Micromachining of Capillary Electrophoresis Injectors and Separators on Glass Chips and Evaluation of Flow at Capillary Intersections”, Analytical Chemistry, vol. 66, No. 1, pp. 177-184, Jan. 1, 1994.

LandOfFree

Say what you really think

Search LandOfFree.com for the USA inventors and patents. Rate them and share your experience with other people.

Rating

Particle analyzer and methods for use thereof does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Particle analyzer and methods for use thereof, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Particle analyzer and methods for use thereof will most certainly appreciate the feedback.

Rate now

     

Profile ID: LFUS-PAI-O-3874617

  Search
All data on this website is collected from public sources. Our data reflects the most accurate information available at the time of publication.