Partially modified, retro-inverso neurotensin analogs

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Peptide containing doai

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530327, 530328, A61K 3702, C07K 708

Patent

active

047161493

ABSTRACT:
Pharmacologically active, partially retro-inverso, neurotensin-like peptides lasting longer than the natural hormone, corresponding to the formula ##STR1## wherein R.sup.1 and R.sup.2 are straight or branched (C.sub.1 -C.sub.7) alkyl radicals.
The new compounds are useful as vasodilating and hypotensive agents.

REFERENCES:
patent: 3929756 (1975-12-01), Leeman et al.
patent: 4110321 (1978-08-01), Folkers
patent: 4331661 (1982-05-01), Marki et al.
patent: 4439359 (1984-03-01), Holly et al.
patent: 4439360 (1984-03-01), Verdini et al.
patent: 4613586 (1986-09-01), Barchas et al.
Chem. Abstr., vol. 104, (1986), 103113.

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