Partially methylated cyclodextrins and process for producing the

Details Partially methylated cyclodextrins and process for producing the Partially methylated cyclodextrins and process for producing the

1987-02-27

1988-05-24

Griffin, Ronald W.

Organic compounds -- part of the class 532-570 series

Organic compounds

Carbohydrates or derivatives

C08B 3700

Patent

active

047467347

ABSTRACT:
Partially methylated cyclodextrins with enhanced solubility in water have an average degree of methylation of hydroxyl groups at different positions in all the glucose units involved of about 53-64% for the 2-position, about 38-51% for the 3-position and about 70-100% for the 6-position. The partially methylated cyclodextrins are prepared by reacting .beta.-cyclodextrin with more than about 30 equivalent proportions based on the .beta.-cyclodextrin of dimethyl sulfate and more than about 30 equivalent proportions of an alkali metal hydroxide, wherein the concentration of reactants is greater than 10% (wt/wt).

REFERENCES:
patent: 4542211 (1985-09-01), Szejtli et al.

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