Organic compounds -- part of the class 532-570 series – Organic compounds – Carbohydrates or derivatives
Patent
1995-04-18
1997-05-27
Kunz, Gary L.
Organic compounds -- part of the class 532-570 series
Organic compounds
Carbohydrates or derivatives
536110, 536124, C08B 3716, A61K 31715
Patent
active
056333684
ABSTRACT:
Partially acylated cyclodextrins of the formula I ##STR1## where R denotes hydrogen or R1, wherein R1 can be identical or different and denotes acetyl, propionyl, butyryl, 2-alkoxyacetyl, 2-chloroacetyl, 2-fluoroacetyl, 2-N-acetylaminoacetyl, methacryloyl or acryloyl, and the DS for R1, measured by means of .sup.1 H NMR spectroscopy, is between 0.30 and 1.20; and a process for preparing partially acylated .beta.-cyclodextrins and also a process for their use.
REFERENCES:
patent: 5008386 (1991-04-01), Szab o et al.
patent: 5096893 (1992-03-01), Pitha et al.
patent: 5183883 (1993-02-01), Tanaka et al.
patent: 5198429 (1993-03-01), K onig et al.
patent: 5492947 (1996-02-01), Wood et al.
Alan P. Croft, Richard A. Bartsch Tetrahedron vol. 39, No. 9, pp. 1417-1474, 1983, Pergamon Press "Synthesis of Chemically Modified Cyclodextrins".
Fang-yu Liu, Dane O. Kildsig, Ashim K. Mitra, "Drug Development and Industrial Pharmacy", 18 (15), 1599-1612 (1992), Complexation of 6-Acyl-O-.beta.-Cyclodextrin Derivatives with Steroids-Effects of Chain-Length and Substitution Degree.
Cyclolab R&D Laboratory Ltd. Budapest, Hungary, Sample Specification ID-No. CY-2002.1 "Acylated .beta.-cyclodextrin" 1993.
CA 117:258209, 1992.
CA 119:145682, 1993.
P. Mischnik New Trends in Cyclodextrins and Derivatives, Dominique Duchene, Chapter 7, "Analysis of the substitution pattern of chemically modified cyclodextrins", Editions des Santes, Paris, no date available.
Klaus Balser et al. "Cellulose Esters", Ullmann's Encyclopedia of Industrial Chemistry, vol. A5, 5th Edition Ed. E. Gerhartz, VCH Verlagsgesellschaft Weinheim 1986, pp. 419-459.
Journal of the American Society, vol. 71, No. 1, Jan. 26, 1949 DC US, pp. 353-356, D. French et al., "Studies on the Schardinger Dextrins", p. 355, right column last para.
Database WPI Week 9407, Derwent Publications Ltd. London, GB An053986 "New (2,3 or 6 or 2,6 or 3,6-acetyl) cyclodextrins" & JP-A-06009709 (Toppan Printing Co. Ltd) Jan. 18, 1994.
Chemical Abstracts, vol. 119 No. 14, Oct. 4, 1993, Columbus, Ohio US Abstract No. 145682j; Uemasu Jsatiu "Trapping of Organic halides using Cyclodextrin derivatives" JP-A-05031212 (Kogyo Gijutsuin), Feb. 9, 1993.
Consortium f ur elektrochemische Industrie GmbH
Fonda Kathleen Kahler
Kunz Gary L.
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