Partial synthesis process for preparing (+) -vincamine and relat

Chemistry: electrical and wave energy – Processes and products – Processes of treating materials by wave energy

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B01J 1912

Patent

active

044002491

ABSTRACT:
A process of partial synthesis of vincamine and related indolic alkaloids for use as the active principal ingredient in drugs for treatment of diseases of the circulatory system and the central nervous system. The process includes the technique of activating oxygen in the elementary state in situ into an excited singlet state for chemical reaction by subjecting a reaction mixture to gaseous oxygen blowing under substantially ambient temperature and pressure conditions while effecting irradiation of the mixture by a light source. Operating conditions of the partial synthesis process are simplified, treatment times are reduced, and conversion yields are high.

REFERENCES:
patent: 4230854 (1980-10-01), Beacco et al.

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