Chemistry: molecular biology and microbiology – Spore forming or isolating process
Patent
1995-06-06
1998-12-01
Lankford, Blaine
Chemistry: molecular biology and microbiology
Spore forming or isolating process
4352401, 4352403, 43524031, 424 931, 424 937, 800 2, 119174, C12N 500
Patent
active
058437541
ABSTRACT:
A process of parthenogenic activation of mammalian oocytes which includes increasing intercellular levels of divalent cations in the oocyte; and reducing phosphorylation of cellular proteins in the oocyte. One method of accomplishing this is by introducing Ca.sup.2+ free cation, such as ionomycin, to the oocyte and then preventing phosphorylation of the cellular proteins within the oocyte by adding a serine-threonine kinase inhibitor, such as 6-dimethylaminopurine (DMAP).
REFERENCES:
patent: 4994384 (1991-02-01), Prather et al.
patent: 5057420 (1991-10-01), Massey et al.
patent: 5096822 (1992-03-01), Rosenkrans
patent: 5160312 (1992-11-01), Voelkel
patent: 5366888 (1994-11-01), Fry et al.
patent: 5453366 (1995-09-01), Sims et al.
Collas, P. and Robl, J.M. 1990 "Factors Affecting the Efficiency of Nuclear Transplantation in the Rabbit Embryo." Biol. Reprod. 43:877-884.
Cuthbertson, K.S.R. 1983. "Parthenogenic Activation of Mouse Oocytes in Vitro With Ethanol and Benzyl Alcohol." J. Exp. Zool. 226:311-314.
First, N.L., Leibfried-Rutledge, M.L., Northey, D.L. and Nuttleman, P.R. 1992. "Use of in Vitro Matured Oocytes 24 Hr of Age in Bovine Nuclear Transfer." Theriogenology 37:211.
First, N.L. and Prather, R.S. 1991. "Genomic Potential in Mammals." Differentiation, 48:108.
Fissore, R.A. and Robl, J.M. 1992. "Intracellular Ca2+ Response of Rabbit Oocytes to Electrical Stimulation." Mol. Reprod. Dev. 32:9-16.
Graham, C.F. 1969. "The Fusion of Cells with One-- and Two-Cell Mouse Embryos." Wistar Inot. Symp. Monogr., 9:19.
Graham, C.F. 1970. "Parthenogenic Mouse Blastocytes." Nature 242:475-476.
Graham, C.F. 1974. "The Production of Parthenogenetic Mammalian Embryos and Their Use in Biological Research." Biol. Rev. 49:399-422.
Gray, K.R., Bondioli, K.R., and Betts, C.L. 1991. "The Commercial Application of Embryo Splitting in Beef Cattle." Theriogenology 35:37-45.
Kaufman, M.H. 1981. "Parthonogenesis: a System Facilitating Understanding of Factors that Influence Early Mammalian Development." Prog. in Anat., vol. 1, 1-34.
Kline, D. and Kline, J.T. 1992. "Repetitive Calcium Transients and the Role of Calcium in Exocytosis and Cell Cycle Activation in the Mouse Egg." Dev. Biol. 149:80-89.
Kubiak, J. 1989. "Mouse Oocytes Gradually Develop the Capacity for Activation during the Metaphase II Arrest." Dev. Biol. 136:537-545.
Masui, Y. and Markert, C.L. 1971. "Cytoplasmic Control of Nuclear Behavior During Meiotic Maturation of Frog Oocytes." J. Exp. Zool. 177, 129-146.
McGrath, J. and Solter, D. 1983. "Nuclear Transplantation in the Mouse Embryo by Microsugery and Cell Fusion." Science, vol. 220, 1301-1302.
Nagai, T. 1987. "Parthenogenetic Activation of Cattle Follicular Oocytes in Vitro with Ethanol." Gamet Res. 16:243-249.
Nurse, P. 1990. "Universal Control Mechanism Regulating Onset of M-Phase." Nature 344:503-508.
Onodera, M. and Tsunoda, Y. 1989. "Parthenogenetic Activation of Mouse and Rabbit Eggs by Electric Stimulation In Vitro." Gamet Res. 22:277-283.
Ozil, J.P. 1990. "The Parthenogenetic Development of Rabbit Oocytes After Repetitive Pulsatile Electrical Stimulation." Development 109:117-127.
Rickords, L.F. and White, K.L. 1992. "Electrofusion-Induced Intracellular Ca2+ Flux and its Effect on Murine Oocyte Activation." Mol. Reprod. Dev. 31:152-159.
Siracusa, G., Whittingham, D.G., Molinaro, M. and Vivarelli, E. 1978. "Parthenogenetic Activation of Mouse Oocytes Induced by Inhibitors of Protein Synthesis." J. Embryol. Exp. Morph. 43:157-166.
Sirard, M.A., Parrish, J.J., Ware, C.B., Leibfried-Rutledge, M.L. and First, N.L. 1988. "The Culture of Bovine Oocytes to Obtain Developmentally Competent Embryos." Biol. Reprod. 39:546-552.
Steinhardt, R.A., Epel, D. and Yanagimachi, R. 1974. "Is Calcium Inophore a Universal Activator for Unfertilized Eggs?" Nature 252:41-43.
Stice, S.L. and Robl, J.M. 1990. "Activation of Mammalian Oocytes by a Factor Obtained From Rabbit Sperm." Mol. Reprod. Dev. 25:272-280.
Stice, S.L. and Keefer, C. 1992. "Improved Developmental Rates for Bovine Nucleus Transfer Embryos Using Cold Shock Activated Oocytes." Biol. Reprod. 42 (Suppl. 1):166.
Surani, M.A.H. and Kaufman, M.H. 1977. "Influence of Extracellular Ca2+ and Mg2+ Ions on the Second Meiotic Division of Mouse Oocytes: Relevance to Obtaining Haploid and Diploid Parthenogenetic Embryos." Dev. Biol. 59:86-90.
Swann, K. 1990. "A Cytosolic Sperm Factor Stimulates Repetitive Calcium Increases and Mimics Fertilization in Hamster Eggs." Development 110:1295-1302.
Tarkowski, A.K., Witkowska, A. and Nowicka, J. 1970. "Experimental Parthenogenesis in the Mouse." Nature 226:162-165.
Tarkowski, A.K. 1975. "Induced Parthenogenesis in the Mouse." (C.L. Markert, E.J. Papaconstantinon, eds.), pp. 107-109, New York: Academic Press.
Ware, C.B., Barnes, F.L., Maiki-Laurila, M. and First, N.L. 1989. "Age Dependence of Bovine Oocyte Activation." Gamete Res. 22:265-275.
Whitaker, M. and Irvine, F.R. 1984. "Inositol 1,4,5-Triphosphate Microinjection Activates Sea Urchin Eggs." Nature (London) 312:636-639.
Yang, X., Jiang, S. and Shi, Z. 1992. "Improved Activation by Combined Cycloheximide and Electric Pulse Treatment of Bovine follicular Oocytes Matured In Vitro for 23-24 House." Biol. Reprod. 42 (Suppl. 1): 117.
Yang, X., Zhang, L., Kovacs, A. Tobback, C. and Foote, R.H. 1990. "Potential of Hypertonic Medium Treatment for Embryo Micromanipulation: II. Assessment of Nuclear Tranplantation Methodology, Isolation, Subzona Insertion, and Electrofusion of Blastomeres to Intact or Functionally Enucleated Oocytes in Rabbits." Mol. Reprod. Dev. 27:118-129.
Yang, X., Jiang, S. and Foote, R.H. 1991. "Nuclear Transfer in Rabbits and Cattle by Electric Pulse-Induced Fusion of Blastomeres to Enucleated Oocytes." Theriogenology 35:298 (abs).
Leibfried-Rutledge M. Lorraine
Northey David L.
Stice Steven L.
Susko-Parrish Joan L.
ABS Global, Inc.
Lankford Blaine
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