Parenterally administrable drug having thrombolytic activity and

Chemistry: natural resins or derivatives; peptides or proteins; – Proteins – i.e. – more than 100 amino acid residues – Glycoprotein – e.g. – mucins – proteoglycans – etc.

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Details

424 941, 424 9463, 424 9464, C07K 300, A61K 3843, A61K 3848

Patent

active

055809626

ABSTRACT:
A thrombolytic, parenterally administrable drug containing activated protein C is provided for. The drug is free of serum amyloid P, thrombin activity, infectious agents and antibodies against protein C and activated protein C.

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O. Taby, J. Chabbat and M. Steinbuch, "Inhibition of Activated Protein C by Aprotinin and the Use of the Insolubilized Inhibitor for its Purification"; Thrombosis Research 59: 27-35, 1990.
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