Parenteral solutions containing metolazone

Details Parenteral solutions containing metolazone Parenteral solutions containing metolazone

1995-02-13

1997-05-27

Weddington, Kevin E.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Para-n-benzene - sulfoxy-n containing doai, and said benzene...

514258, 514259, A61K 3163, A61K 31505

Patent

active

056332408

ABSTRACT:
Disclosed herein are parenteral solutions containing 7-halo-1,2,3,4-tetrahydro-3-aryl-6-quinazoline sulfonamide in Tris or Bis-Tris or Tris buffer useful in the treatment of hypertension, heart disease and heart failure and renal disease. Also disclosed are methods for preparing such solutions.

REFERENCES:
patent: 2174242 (1939-09-01), Hass et al.
patent: 2485982 (1949-10-01), McMillan
patent: 3058882 (1962-10-01), St urm et al.
patent: 3360518 (1967-12-01), Shetty
patent: 3557111 (1971-01-01), Shetty
patent: 5124152 (1992-06-01), Biringer et al.
Windholz et al., The Merck Index, 10th Ed. (Merck & Co., Inc) (New Jersey) 1983, p. 615, ab. No. 4186 and p. 1395, ab. No. 9575.

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