Parathion hydrolase analogs and methods for production and purif

Details Parathion hydrolase analogs and methods for production and purif Parathion hydrolase analogs and methods for production and purif

1994-11-01

1996-01-16

Patterson, Jr., Charles L.

Chemistry: molecular biology and microbiology

Micro-organism, per se ; compositions thereof; proces of...

Bacteria or actinomycetales; media therefor

435196, 435 691, 435 698, 435 711, 435 712, 4351723, 43525231, 43525233, 43525234, 43525235, 4352541, 43525421, 4353201, 935 10, 935 14, 935 29, 935 38, 935 56, 935 73, 536 232, C12N 1555, C12N 1563, C12N 121, C12N 916

Patent

active

054847281

ABSTRACT:
The present invention provides a novel gene encoding DNA sequence for the expression of parathion hydrolase and an analog thereof, and methods for preparing such compounds. In a particularly preferred embodiment, the present invention relates to a parathion hydrolase gene encoding sequence in which twenty-eight amino acids are deleted from the N-terminal amino acid sequence of parathion hydrolase. The novel gene encoding parathion hydrolase encoding sequence is useful for production of the mature or processed parathion hydrolase and a methionine (-1) analog thereof.

REFERENCES:
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