Drug – bio-affecting and body treating compositions – Antigen – epitope – or other immunospecific immunoeffector – Parasitic organism or component thereof or substance...
Patent
1995-03-20
1998-09-08
Sidberry, Hazel F.
Drug, bio-affecting and body treating compositions
Antigen, epitope, or other immunospecific immunoeffector
Parasitic organism or component thereof or substance...
4241841, 4241851, 424 9464, 530350, A61K 3900, A61K 39002, C07K 1400, C07K 1444
Patent
active
058042008
ABSTRACT:
Immunogens derived from proteins isolatable from the L3 and L4 larval stages of nematodes parasitic in mammals, and including a protein of about 20.5 kD, are disclosed. The proteins of the invention are identified using biological materials verified to destroy or impair the parasitic nematode in an in vivo incubator. Cells, serum or fractions thereof obtained from immune natural hosts are validated in a method wherein a recoverable implant of the parasitic nematodes is used to assess the protective effect when these materials are provided passively to the animal incubator.
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Frank Glenn R.
Grieve Robert B.
Colorado State University Research Foundation
Heska Corporation
Sidberry Hazel F.
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