Parasitic helminth venom allergen antigen 5-like genes and prote

Details Parasitic helminth venom allergen antigen 5-like genes and prote Parasitic helminth venom allergen antigen 5-like genes and prote

1995-05-23

1998-08-04

Hutzell, Paula K.

Chemistry: molecular biology and microbiology

Micro-organism, tissue cell culture or enzyme using process...

Recombinant dna technique included in method of making a...

435 691, 435 693, 4352523, 536 231, 536 234, 536 235, 530350, 530300, 5303871, 4242651, 4241511, 4241911, 4241301, C12P 2100, C07H 2104, C07K 100, A61K 3900

Patent

active

057891940

ABSTRACT:
The present invention relates to parasitic helminth venom allergen antigen 5-like proteins; to parasitic helminth venom allergen antigen 5-like nucleic acid molecules, including those that encode such proteins; and to antibodies raised against such proteins. The present invention also includes methods to obtain such proteins, nucleic acid molecules and antibodies. Also included in the present invention are therapeutic compositions comprising such proteins, nucleic acid molecules and/or antibodies, as well as the use of such therapeutic compositions to protect animals from diseases caused by parasitic helminths.

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Brilliantes et al., 1994, Cell, 77:513-523.
Hotez et al., 1994, J. Infectious Dis., 170:918-926.
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Chamekh et al., 1990, J. Immunological Meth., 134:129-137.
Fang et al., 1988, Proc. Natl. Acad. Sci. USA, 85:895-899.
Lightowlers et al., 1989, Mol. Biochem. Parasitol., 37:171-182.
Lu et al., 1993, J. Immunol., 150:2823-2830.
Valdez et al., 1994, J. Parasitol. 80(6):931-936.

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