Parasitic helminth macrophage inhibitory factor nucleic acid mol

Details Parasitic helminth macrophage inhibitory factor nucleic acid mol Parasitic helminth macrophage inhibitory factor nucleic acid mol

1995-11-16

1997-10-28

Horlick, Kenneth R.

Chemistry: molecular biology and microbiology

Micro-organism, tissue cell culture or enzyme using process...

Using tissue cell culture to make a protein or polypeptide

4351723, 4352402, 4352523, 4353201, 536 235, 536 2431, 536 2433, C07H 2104, C12P 2102

Patent

active

056817240

ABSTRACT:
The present invention relates to parasitic helminth macrophage migration inhibitory factor (MIF) proteins; to parasitic helminth MIF nucleic acid molecules, including those that encode such MIF proteins; to antibodies raised against such MIF proteins; and to compounds that inhibit parasitic helminth MIF activity. The present invention also includes methods to obtain such proteins, nucleic acid molecules, antibodies, and inhibitory compounds. Also included in the present invention are therapeutic compositions comprising such proteins, nucleic acid molecules, antibodies and/or inhibitory compounds as well as the use of such therapeutic compositions to protect animals from diseases caused by parasitic helminths.

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