Parasitic helminth larval thiol specific antioxidant proteins, n

Details Parasitic helminth larval thiol specific antioxidant proteins, n Parasitic helminth larval thiol specific antioxidant proteins, n

1998-01-07

2000-02-29

Minnifield, Nita

Chemistry: natural resins or derivatives; peptides or proteins;

Proteins, i.e., more than 100 amino acid residues

530300, 4241841, 4242651, 514 8, 514 44, 536 231, C07K 100, A61K 3900, A61K 3902, A61K 3816, A01N 4304

Patent

active

060310774

ABSTRACT:
The present invention relates to parasitic helminth thiol specific antioxidant (TSA) larval proteins; to parasitic helminth larval TSA nucleic acid molecules, including those that encode such TSA proteins; to antibodies raised against such TSA proteins; and to compounds that inhibit parasitic helminth larval TSA activity. The present invention also includes methods to obtain such proteins, nucleic acid molecules, antibodies, and inhibitory compounds. Also included in the present invention are therapeutic compositions comprising such proteins, nucleic acid molecules, antibodies and/or inhibitory compounds as well as the use of such therapeutic compositions to protect animals from diseases caused by parasitic helminths.

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