Parasitic helminth asparaginase proteins, nucleic acid molecules

Details Parasitic helminth asparaginase proteins, nucleic acid molecules Parasitic helminth asparaginase proteins, nucleic acid molecules

1999-09-16

2000-12-26

Chan, Christina Y.

Chemistry: molecular biology and microbiology

Measuring or testing process involving enzymes or...

Involving antigen-antibody binding, specific binding protein...

5303886, 5303892, 4241511, 4241391, G01N 3353, G01N 33569, C07K 1600, C12P 2108, A61K 39395

Patent

active

061657352

ABSTRACT:
The present invention relates to: parasitic helminth asparaginase proteins; parasitic helminth asparaginase nucleic acid molecules, including those that encode such asparaginase proteins; antibodies raised against such asparaginase proteins; and compounds that inhibit parasitic helminth asparaginase activity. The present invention also includes methods to obtain such proteins, nucleic acid molecules, antibodies, and inhibitory compounds. Also included in the present invention are therapeutic compositions comprising such proteins, nucleic acid molecules, antibodies and/or inhibitory compounds as well as the use of such therapeutic compositions to protect animals from diseases caused by parasitic helminths.

REFERENCES:
Bussolati et al., 1994, FASEB Journal 8(4-5), p. A95, Abstract No. 549.
Dunlop et al., 1978, The Journal of Biological Chemistry 253:4, pp. 1297-1304.
Jerlstrom et al., Gene 78, pp. 37-46. 1989.
Mesas et al., 1990, Journal of General Microbiology 136, pp. 515-519.
Rozalska, Malgorzata, 1989, Acta Microbiologica Polonica 38, pp. 233-245.
Sobis et al., 1991, Acta Microbiologica Polonica 40:3/4, pp. 143-452.
Sun et al., 1991, Journal of Bacteriology 173: 12, pp. 3831-3845.
Tanaka et al., 1988, The Journal of Biological Chemistry 263, pp. 8583-8591.
Tiwari et al., 1996, Indian Journal of Biochemistry & Biphysics 33, pp. 371-376.
Tsavdaridis et al., 1991, Biochemistry International 24:2, pp. 281-290.
Wilson et al., 1994, Nature 368, pp. 32-38.
Zhang et al., 1995, Comp. Biochem. Pjysiol. 112B:4, pp. 607-612.
Grantham et al., 1986, Parasitology, vol. 93, pp. 481-193.
Dorner et al., 1993, Genbank Accession No. Q41029.
Feng, et al., 1985, J. Mol. Evol. 21, pp. 112-125.
Johnson, et al., 1993, J. Mol. Biol. 233, pp. 716-738.
Meinkoth, et al., 1984, Analytical Biochemistry 138, pp. 267-284.

Affiliated with

Also associated with

Rating

Parasitic helminth asparaginase proteins, nucleic acid molecules does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Parasitic helminth asparaginase proteins, nucleic acid molecules, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Parasitic helminth asparaginase proteins, nucleic acid molecules will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-993293