Paramagnetic metal-phthalocyanine complex compounds and...

Organic compounds -- part of the class 532-570 series – Organic compounds – Heterocyclic carbon compounds containing a hetero ring...

Reexamination Certificate

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C540S128000, C540S123000, C540S140000, C540S125000, C540S139000, C514S191000, C514S185000, C514S163000, C514S410000, C536S029110, C424S009430, C424S009440, C424S009300, C424S009340, C424S009350, C424S001650

Reexamination Certificate

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07005517

ABSTRACT:
The present invention provides a novel paramagnetic metal-phthalocyanine complexes and pharmaceutically acceptable salts thereof, which are useful as contrast agents for MRI(Magnetic Resonance Imaging), diagnostic X-ray imaging and computed tomography(CT).The present invention also provides contrast agents for imaging, comprising the new paramagnetic metal-phthalocyanine complexes. The new contrast agents of the present invention show high imaging enhancement effects at lower concentration and are safer than the previously reported contrast agents.

REFERENCES:
patent: 5622685 (1997-04-01), Sinn et al.
Saini, K.K. et al., “MnPcS4: A New MRI Contrast Enhancing Agent for Tumor Localisation in Mice”, Magnetic Resonance Imaging, vol. 13, No. 7, pp. 985-990 (1995).

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