Paralytic peptide for use as a insecticide

Details Paralytic peptide for use as a insecticide Paralytic peptide for use as a insecticide

2011-08-23

2011-08-23

Swope, Sheridan (Department: 1652)

Chemistry: natural resins or derivatives; peptides or proteins;

Peptides of 3 to 100 amino acid residues

Reexamination Certificate

active

08003754

ABSTRACT:
The invention relates to a method of killing or immobilizing an insect comprising administering to the insect a low molecular weight peptide isolated from the submaxiliary saliva glands of shrews of the speciesBlarina. The invention further relates to an insecticide composition comprising such a peptide.

REFERENCES:
patent: 5424286 (1995-06-01), Eng
patent: 6326020 (2001-12-01), Kohane et al.
patent: 7119168 (2006-10-01), Stewart et al.
patent: 7273850 (2007-09-01), Stewart et al.
patent: 7485622 (2009-02-01), Stewart et al.
patent: 7745588 (2010-06-01), Stewart et al.
patent: 2006/0217302 (2006-09-01), Stewart et al.
patent: 10236963 (1998-08-01), None
Steeves, Active components of the venumous saliva of the short-tailed shrew (Blarina brevicauda). Bachelor of Science Thesis. Department of Biology, Mount Allison University. May 2002 (presented Apr. 26, 2002).
Amersham, Protein Purification Handbook, 1999.
Cai, Z, et al., “Solution Structure of BmBKTx1, a new BKca1Channel Blocker from the Chinese Scorpion Buthus martensi Karsch,” Biochemistry, Vo. 433, No. 13, pp. 3764-3771, 2004.
Christenbury, P., “A Study of the Ecology ofBiarina brevicaudiain North Carolina ando f the Effect of Shrew Toxin on the Liver and Kidneys of Mice.” A thesis submitted to the Graduate Faculty of Wake Forest College in parcial fulfillment of the requirements for the negree of Master of Arts in the Department of Biology, Aug. 1966.
Dekker, E. et al., “The epithelial calcium channels, TRPV5 and TRPV6: from identification towards regulation,” Cell Calcium, vol. 33, pp. 497-507, 2003.
Dufton, M., “Venomous Mammals,” Pharmac. Ther. vol. 53, pp. 199-215, 1992.
GenCore version 5.1.7, pp. 3-4 (Result 5), Feb. 1, 1996 (created, last sequence update), Oct. 25, 2004 (last annotation update).
George, S. et al., “Blarina brevicuada,” Mammalian Species, No. 261, pp. 1-9, 3 Figures, 1986.
Kita, M. et al., “Blarina toxin, a mammalian lethal venom from the short-tailed shrewBlarina brevicuada: isolation and characterization,” Proceedings of the National Academy of Sciences of the United States of America, vol. 101, No. 20, pp. 7542-7547, 2004.
Lecchi, P. et al., “The Structure of Synenkephalin (Pro-Enkephalin1-73) Is Dictated by Three Disulfide Bridges,” Biochemical and Biophysical Research Communications, vol. 232, pp. 800-805, 1997.
Martin, I., “Venom of the Short-Tailed Shrew (Blarina brevicuada) As an Insect Immobilizing Agent,” Journal of Mammalogy, vol. 62, No. 1, p009U7p. 189-192, 1978.
Montell, C., “The venerable inveterate invertebrate TRP channels,” Cell Calcium, vol. 33, pp. 409-417, 2003.
Mount Allison University, “Potent Peptide Paralytic Agent,” Version 1, Jun. 2003.
Mount Allison University, “Potent Peptide Paralytic Agent,” Version 2, Jul. 2003.
Pearson, O., “On the cause and nature of poisonous action produced by the bite of a shrew (Blarina brevicuada),” Journal of Mammalogy, pp. 159-166, 1942.
Peng, J. et al., “CaT1 Expression Correlates with Tumor Grade in Prostate Cancer,” Biochemical and Biphysical Research Communications, vol. 282, pp. 729-734, 2001.
Peng, J. et al. “Human Calcium Transport Protein CaT1,” Biochemical and Biophysical Research Communications, vol. 278, pp. 326-332, 2000.
Pohl, M. et al., “Molecular Cloning of the Helodermin and Exendin-4 cDNAs in the Lizard,” The Journal of Biological Chemistry, vol. 273, No. 16, pp. 9778-9784, 1998.
Pucek, M., Chemistry and Pharmacology of Insertivore Venoms, Chapter 3 of Venomous Animals and Their Venoms, edited by W. Bucheri, Academic Press, New York—London, pp. 43-50, 1968.
Smart P., “Shrew Saliva Spells Relief? Prof. Jack Stewart makes breakthrough medical discovery,” The Argosy, Jan. 16, 2003.
Tomasi, T., “Function of Venom in the Short-Tailed ShrewBlarina brevicuada,” Journal of Mammalogy, vol. 59, No. 4, pp. 852-854, 1978.
Zhuang, L. et al., “Calcium-Selective Ion Channel, CaT1, is Apically Localized in the Gastrointestinal Tract Epithelia and is Aberrantly Expressed in Human Malignancies,” Laboratory Investigation, vol. 82, No. 12, pp. 1755-1764, 2002.

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